Hyperproduction of TEM-1 beta-lactamase in clinical isolates of Escherichia coli serotype O15
نویسندگان
چکیده
منابع مشابه
Clinical characteristics of bloodstream infections due to ampicillin-sulbactam-resistant, non-extended- spectrum-beta-lactamase-producing Escherichia coli and the role of TEM-1 hyperproduction.
Ampicillin-sulbactam is commonly used as an empirical therapy for invasive infections where Escherichia coli is a potential pathogen. We evaluated the clinical and microbiologic characteristics of bloodstream infection due to E. coli, with focus on cases that were nonsusceptible to ampicillin-sulbactam and not producing extended-spectrum β-lactamase (ESBL). Of a total of 357 unique bacteremic c...
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background : ampc β-lactamases are important cephalosporinases chromosomally encoded in many of enterobacteriaceae and a few other organisms where they mediate resistance to cephalothin, cefazolin, cefoxitin and penicillins. the six different families of plasmid-mediated ampc β-lactamases have been described, but no phenotypic test can discriminate among them. ampc multiplex pcr has been succ...
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Background: The isolation of the TEM gene in Pseudomonas aeruginosa and Escherichia coli and the antibiotic resistance pattern provides useful information on the epidemiology and factors involved in these infections. Aim: The aim of this study was to evaluate antibiotic resistance and abundance of a beta-lactamase gene (TEM) in P.aeruginosa and E.coli isolated from clinical specimens by the po...
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background : ampc beta lactamases play a significant role in creating resistance to third generation cephalosporins worldwide. they mostly express on chromosome of enterobacteriaceae especially escherichia coli and cause consequential problem in clinical treatment and lead to failure in diagnosis and phenotypic test recommended by clinical and laboratory standards institute. methods : total...
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1. Chambers HF. Methicillin resistance in staphylococci: molecular and biochemical basis and clinical implications. Clin Microb Rev 1997; 10: 781–91. 2. Brown DFJ. Detection of methicillin/oxacillin resistance in staphylococci. J Antimicrob Chemother 2001; 48 Suppl S1: 65–70. 3. Skov R, Smyth R, Larsen AR et al. Evaluation of cefoxitin 5 and 10 mg discs for the detection of methicillin resistan...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 1990
ISSN: 0378-1097
DOI: 10.1016/0378-1097(90)90016-j